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Skullcapflavone II
CAS No. 55084-08-7
Skullcapflavone II ( —— )
产品货号. M22798 CAS No. 55084-08-7
Skullcapflavone II 是一种从黄芩中提取的黄酮类化合物，黄芩是一种广泛用于抗炎和抗癌治疗的草药。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2025 | 有现货 |
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| 10MG | ￥2981 | 有现货 |
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| 25MG | ￥5046 | 有现货 |
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| 50MG | ￥7185 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Skullcapflavone II
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Skullcapflavone II 是一种从黄芩中提取的黄酮类化合物，黄芩是一种广泛用于抗炎和抗癌治疗的草药。
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产品描述Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy.?Skullcapflavone II may have therapeutic potential for the treatment of allergic asthma.Skullcapflavone II regulates osteoclast differentiation, survival, and function.?Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG.
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体外实验Skullcapflavone II inhibits osteoclastogenesis with decreased activation of MAPKs, Src, and cAMP response element-binding protein (CREB), which have been known to be redox sensitive. Skullcapflavone II decreases reactive oxygen species by scavenging them or activating nuclear factor-erythroid 2-related factor 2 (Nrf2), and its effects were partially reversed by hydrogen peroxide cotreatment or Nrf2 deficiency.
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体内实验Skullcapflavone II, a potential bradykinin antagonist, reduces the major pathophysiological features of allergic asthma, at least in part by acting on TGF-β1/Smad signaling pathways.
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同义词——
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通路Others
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靶点Other Targets
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受体TGFβ|COX
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研究领域——
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适应症——
化学信息
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CAS Number55084-08-7
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分子量374.35
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分子式C19H18O8
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (133.57 mM)
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SMILESCOC1=C2C(C(C=C(C3=C(C=CC=C3O)OC)O2)=O)=C(O)C(OC)=C1OC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Lee Y H , Seo E K , Lee S T . Skullcapflavone II Inhibits Degradation of Type I Collagen by Suppressing MMP-1 Transcription in Human Skin Fibroblasts[J]. International Journal of Molecular Sciences, 2019, 20(11).
产品手册
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